HDAC4, GST-tag, His-tag Recombinant 50004 from BPS Bioscience, Inc.

Product Specs
ItemHDAC4, GST-tag, His-tag Recombinant
CompanyBPS Bioscience, Inc.
Price $460.00Supplier Page View Company Product Page
Catalog Number50004
Size10 µg
Conjugate/TagN-terminal GST-tag, C-terminal His-tag
FormatAqueous buffer solution
Molecular Weight76 kDa
SpeciesHuman
Domain/Region/Terminus627-1084 (end)
NCBI Full Gene Namehistone deacetylase 4
NCBI Gene AliasesNEDCHF, HD4, BDMR, HDAC-A, HDACA, HA6116, NEDCHID, HDAC-4, AHO3
TypeProtein
Source/Expression SystemSf9 cells
insect
ApplicationsUseful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

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BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

(1) Reprogramming of bacterial virulence by lysine acetylationNat CommunApril 27, 2026Ole Schmöker, Britta Girbardt, Sabrina Schulze, Gottfried J. Palm, Leona Berndt, Jens Hoppen, Nilüfer Kara, Xenia Schöps, Ruba Al-Abdulla, Klara Garz, et al.no. 50003), HDAC4 (aa 627-1084, N-terminal GST-tag and C-terminal His6-tag, BPS Bioscience, cat no. 50004), HDAC6 (full length, N-terminal GST-tag, Sigma-Aldrich, cat no.382180), HDAC7 (aa 518-952, N-terminal

(2) Preclinical Characterization of SDFZ‐8, a Highly Potent HDAC1 Inhibitor, for Cancer ImmunotherapyMedComm (2020)December 1, 2025Yi Zhou, Jintong Du, Xue Li, Huajun Zhao, Junxin Xue, Yuchen Liu, Xinying Yang, Jinming Yu, Xuben Hou, Hao Fang(BPS BIOSCIENCE Inc; 50052), HDAC3/NCOR1 complex (BPS BIOSCIENCE Inc; 50003), HDAC4 (BPS BIOSCIENCE Inc; 50004), HDAC5 (BPS BIOSCIENCE Inc; 50005), HDAC6 (BPS BIOSCIENCE Inc; 50006), HDAC7 (BPS BIOSCIENCE Inc; 50007),

(3) Development of the First-in-Class FEM1B-Recruiting Histone Deacetylase DegradersJournal of Medicinal ChemistryJanuary 23, 2025Felix Feller, Irina Honin, Martina Miranda, Heiko Weber, Svenja Henze, Maria Hanl, Finn K. Hansen50051, BPS Bioscience, San Diego, CA, USA), HDAC2 (Catalog# 50052, BPS Bioscience), HDAC4 (Catalog# 50004, BPS Bioscience), or HDAC6 (Catalog# 50006, BPS Bioscience) were used. The total assay volume of 50

(4) Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6Journal of medicinal chemistryOctober 12, 2023König B, Watson PR, Reßing N, Cragin AD, Schäker-Hübner L, Christianson DW, Hansen FK.(BPS Bioscience, Catalog# 50052); HDAC3/NcoR2 (BPS Bioscience, Catalog# 50003); HDAC4 (BPS Bioscience, Catalog# 50004); HDAC6 (BPS Bioscience, Catalog# 50006) were added. Enzyme and inhibitor were preincubated at 25 °C

(5) Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute LeukemiaJournal of Medicinal ChemistryNovember 24, 2022Nina Reßing, Julian Schliehe-Diecks, Paris R. Watson, Melf Sönnichsen, Abigail D. Cragin, Andrea Schöler, Jing Yang, Linda Schäker-Hübner, Arndt Borkhardt, David W. Christianson, et al.Boc-Lys(Tfa)-AMC (Bachem, Catalog# 4060676, 42.86 μM in assay buffer) and 10 μL of HDAC4 (BPS Bioscience, Catalog# 50004) enzyme solution were added. The total assay volume (50 μL, max. 1% DMSO) was incubated at 37 °C for

(6) High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assaysSTAR ProtocolsMarch 4, 2021Carlos Moreno-Yruela, Christian A. Olsen,BPS Bioscience,Cat#50003 "HDAC4 (aa 627–1,084 with N-terminal GST-tag, C-terminal His-tag)",BPS Bioscience,Cat#50004 "HDAC5 (aa 656–1,122 with C-terminal His-tag)",BPS Bioscience,Cat#50005 HDAC6 (full length with C-terminal

(7) Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylasesNature communicationsJanuary 4, 2021Moreno-Yruela C, Bæk M, Vrsanova AE, Schulte C, Maric HM, Olsen CA.https://doi.org/10.1038/s41467-020-20250-9 pmol/min/µg), HDAC4 (aa 627‒1084, BPS Bioscience, cat. #: 50004, lot 130828-G, purity ≥ 89%, activity ≥ 103225 pmol/min/µg), HDAC6 (full length, BPS Bioscience, cat.

(8) Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 (HDAC6) InhibitorsJournal of Medicinal ChemistryFebruary 14, 2019Katharina Vögerl et al.volume of 30 μL. 5 μL ZMTFAL (150 μM) as fluorogenic substrate, HDAC4 (BPS Bioscience, catalog no. 50004) (0.01 μg/well) in incubation buffer (15 mM Tris-HCl, pH 7.5, 50 mM KH2PO4, 3 mM MgSO4, 10 mM KCl) and

(9) Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscleFEBS LettersApril 28, 2015Douglas D. Lemon, Brooke C. Harrison, Todd R. Horn, Matthew S. Stratton, Bradley S. Ferguson, Michael F. Wempe, Timothy A. McKinseycontrols. To monitor recombinant HDAC4 activity, 15ng of recombinant human HDAC4 (BPS Bioscience; #50004) or PBS blank was added to a 96-well plate. Wells were incubated for 1hr with increasing concentrations

(10) Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironmentCancer researchFebruary 15, 2013Isaacs JT, Antony L, Dalrymple SL, Brennen WN, Gerber S, Hammers H, Wissing M, Kachhap S, Luo J, Xing L, et al.recombinant GST-tagged HDAC4 (i.e., amino acid 627-1085) obtained from BPS Bioscience (San Diego CA, Cat # 50004) added to the mixture which was incubated overnight at 4°. The mixture was centrifuged, pellet washed

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HDAC4, GST-tag, His-tag Recombinant

HDAC4, GST-tag, His-tag Recombinant

HDAC4, GST-tag, His-tag

HDAC4, GST-tag, His-tag Recombinant

HDAC4, GST-tag, His-tag Recombinant from BPS Bioscience, Inc.

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BPS Bioscience, Inc.

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HDAC4, GST-tag, His-tag Recombinant from BPS Bioscience, Inc.

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