Description
Description: FCGRT Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 285 amino acids (22-297 a.a) and having a molecular mass of 32.1kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). FCGRT is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Introduction: Fc Fragment Of IgG Receptor And Transporter also known as FCGRT is a transmembrane glycoprotein with structural homology to MHC class 1 proteins. FCGRT is widely expressed in endothelial and epithelial cells and takes a vital part in IgG homeostasis. Moreover, FCGRT is expressed in neutrophils in addition myeloid antigen presenting cells. FCGRT can enhance IgG-meditated phagocytosis as well as antigen presentation by heses cells, however it promotes the degradation of opsonizing IgG rather than returning it to the circulation