Human c-MET / HGFR Protein (ECD, His & Fc Tag) 10692-H03H from Sino Biological, Inc.

Product Specs
ItemHuman c-MET / HGFR Protein (ECD, His & Fc Tag)
CompanySino Biological, Inc.
Price $1,288.00Supplier Page View Company Product Page
Catalog Number10692-H03H
Conjugate/TagC-human IgG1-Fc, His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe mature recombinant human c-Met/Fc is a disulfide-linked tetramer composed of two proteolytically cleaved α and β subunits. Each α and β together with the C-terminal Fc tag consists of 1155 amino acids and has a predicted molecular mass of 129.5 (α =32.5 + Fc tagged β=97) kDa. The rh c-MET/Fc heterodimer thus migrates with apparent molecular mass of approximately 50.28 kDa and 112.61 kDa respectively in SDS-PAGE under reducing conditions due to glycosylation
SpeciesHuman
Molecule NameMET
Source/Expression SystemHEK293 Cells
Activity1.Immobilized HGF Protein, Human, Recombinant(Cat:10463-HNAS) at 2 µg/mL (100 µL/well) can bind c-MET Protein, Human, Recombinant (ECD, His & hFc Tag) (Cat:10692-H03H), the EC50 is 15-70 ng/mL. 2.Immobilized Recombinant Human c-MET / HGFR Protein (ECD, His & Fc Tag) (Cat: 10692-H03H) at 1 µg/mL (100 µL/well) can bind anti-MET(Research Grade Emibetuzu*mab Biosimilar), the EC50 is 20.4 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS, 8% Trehalose, pH 7.4
Size1 mg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Macrocyclic Peptide-Conjugated Tip for Fast and Selective Molecular Recognition Imaging by High-Speed Atomic Force MicroscopyACS applied materials & interfacesNovember 24, 2021Puppulin L, Kanayama D, Terasaka N, Sakai K, Kodera N, Umeda K, Sumino A, Marchesi A, Weilin W, Tanaka H, et al.

(2) High-Affinity Human Anti-c-Met IgG Conjugated to Oxaliplatin as Targeted Chemotherapy for Hepatocellular CarcinomaFrontiers in oncologyJanuary 1, 2019Ma Y, Zhang M, Wang J, Huang X, Kuai X, Zhu X, Chen Y, Jia L, Feng Z, Tang Q, et al.IgG (41). ELISA For ELISA, 50 μl/well of recombinant human c-Met/ HGFR Protein (Sino Biological #10692-H03H) at 1 μg/mL in PBS was used to coat 96-well plates for 2 h at room temperature, followed by blocking

(3) Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI DomainInternational journal of molecular sciencesSeptember 13, 2017Park H, Kim D, Kim E, Sa JK, Lee HW, Yu S, Oh J, Kim SH, Yoon Y, Nam DH.scFv displaying phage libraries were enriched on 1 µg immobilized human c-Met ECD-Fc (Sino Biological, 10692-H03H, Beijing, China) and mouse c-Met ECD-Fc (Sino Biological, 50622-M02H, Beijing, China) in MaxiSorp™ immune-tubes

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Human c-MET / HGFR Protein (ECD, His & Fc Tag)

Human c-MET / HGFR Protein (ECD, His & Fc Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human c-MET / HGFR Protein (ECD, His & Fc Tag) from Sino Biological, Inc.

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