IL-3 Protein 403-ML-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-3 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $316.00Supplier Page View Company Product Page
Catalog Number403-ML-010
SpeciesMouse
Size10 ug (also 25 ug, 50 ug, 100 ug, 500 ug)
Molecule NameIL-3
NCBI Full Gene Nameinterleukin 3
NCBI Gene AliasesBPA, HCGF, MCGF, PSF, Csfmu, MULTI-CSF, IL-3, Il-3
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemE. coli-derived Recombinant Mouse IL-3 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 25 ug, 50 ug, 100 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) PTEN-loss confers dependence on the guanylate synthesis enzyme IMPDH in T-cell acute lymphoblastic leukemiabioRxiv : the preprint server for biologyDecember 24, 2025Padder RA, Le TL, Hyde E, Rubio MED, Chiles E, Sheshadri N, Mulraney K, Zong WX, Su X, Herranz D, et al.IDEXX BioAnalytics (Columbia, MO), and grown in media supplemented with 10 ng/mL IL-3 (R&D systems #403-ML010). To generate Ba/F3 cells stably expressing non targeting sgRNA (sgCtl) or sgRNA targeting PTEN (sgPTEN),

(2) Function‐driven design of a surrogate interleukin‐2 receptor ligandFEBS LettersDecember 16, 2025Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang YangRPMI‐1640 medium (#11875500BT; Gibco) containing 10% (v/v) FBS and 10 ng·mL−1 recombinant murine IL‐3 (rmIL‐3, #403‐ML‐010; R&D Systems, Minneapolis, MN, USA). Human peripheral blood mononuclear cells (PBMCs; SAILYBIO, Shanghai,

(3) Loss of Function Mouse Models Reveal a Novel Regulatory Function for ULK1 in Myeloproliferative NeoplasmsMolecular and Cellular BiologySeptember 2, 2025Diana Saleiro, Jeremy Q. Wen, Markella Zannikou, Brian Lee, Ewa M. Kosciuczuk, Sarah D. Nehlsen, Adam Munshi, Xintong Chen, Chidera V. Oku, Briana Hryhorysak, et al.StemCell Technologies) supplemented with human LDL (1:500, #02698, StemCell Technologies), mouse IL-3 (10ng/ml, #403-ML-010, R&D Systems), mouse SCF (40ng/ml, #455-MC-020, R&D Systems) and human IL-6 (10ng/ml, #7270-IL-025,

(4) Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potentialNature communicationsAugust 7, 2025Wu R, Salehi F, Redecke V, Ma Z, Marchetti M, Finkelstein D, Xu P, Cheng Y, Queisser KA, Petrey AC, et al.

(5) Ruxolitinib mediated paradoxical JAK2 hyperphosphorylation is due to the protection of activation loop tyrosines from phosphatasesLeukemiaJuly 1, 2025Gorantla SP, Oelschläger L, Prince G, Osius J, Kolluri SB, Maluje Y, Fähnrich A, Ernst N, Barbosa Gulde A, Ludwig RJ, et al.

(6) Selective targeting of oncogenic hotspot mutations of the HER2 extracellular domainNature chemical biologyMay 1, 2025Bang I, Hattori T, Leloup N, Corrado A, Nyamaa A, Koide A, Geles K, Buck E, Koide S.

(7) SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiationCell reportsAugust 27, 2024Chang YH, Yamamoto K, Fujino T, Wang TW, Sugimoto E, Zhang W, Yabushita T, Suzaki K, Pietsch EC, Weir BA, et al.

(8) mTORC1 activity oscillates throughout the cell cycle, promoting mitotic entry and differentially influencing autophagy inductionCell ReportsAugust 27, 2024Jay N. Joshi, Ariel D. Lerner, Frank Scallo, Alexandra N. Grumet, Paul Matteson, James H. Millonig, Alexander J. ValvezanScientific #A5256701), 1% penicillin-streptomycin (Corning #30–002-CI), and 10 ng/mL IL-3 (R&D systems #403-ML-010). METHOD DETAILS Cell cycle synchronization For double thymidine block, cells were treated with

(9) Constant surface area-to-volume ratio during cell growth as a design principle in mammalian cellsbioRxiv : the preprint server for biologyJuly 18, 2024Wu W, Lam AR, Suarez K, Smith GN, Duquette SM, Yu J, Mankus D, Bisher M, Lytton-Jean A, Manalis SR, et al.

(10) Foretinib Is Effective in Acute Myeloid Leukemia by Inhibiting FLT3 and Overcoming Secondary Mutations That Drive Resistance to Quizartinib and GilteritinibCancer researchMarch 15, 2024Wang P, Zhang Y, Xiang R, Yang J, Xu Y, Deng T, Zhou W, Wang C, Xiao X, Wang S.

(11) Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesisScience advancesFebruary 16, 2024Pv A, Mehatre SH, Verfaillie CM, Alam MT, Khurana S.

(12) A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infectionImmunityFebruary 13, 2024Naina Gour, Hwan Mee Yong, Aishwarya Magesh, Aishwarya Atakkatan, Felipe Andrade, Stephane Lajoie, Xinzhong DongNeuropeptide FF,Tocris,Cat#3137 Substance P,Tocris,Cat# 1156 anti-mouse IFNγ,BioXcell,Cat#BE0055 Recombinant Mouse IL-3,R&D systems,Cat# 403-ML-010 Recombinant Mouse SCF,R&D systems,Cat# 455-MC-010 Recombinant Murine IFNγ,Peprotech,Cat# 315-05 Recombinant Murine IL-4

(13) mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy inductionbioRxiv : the preprint server for biologyFebruary 7, 2024Joshi JN, Lerner AD, Scallo F, Grumet AN, Matteson P, Millonig JH, Valvezan AJ.

(14) Type 3 secretion system induced leukotriene B4 synthesis by leukocytes is actively inhibited by Yersinia pestis to evade early immune recognitionPLoS pathogensJanuary 1, 2024Brady A, Sheneman KR, Pulsifer AR, Price SL, Garrison TM, Maddipati KR, Bodduluri SR, Pan J, Boyd NL, Zheng JJ, et al.

(15) Staphylococcus aureus δ-Toxin Induces Ca(2+) Influx-Independent Degranulation of Murine Cultured Mast CellsBiological & pharmaceutical bulletinJanuary 1, 2024Liu K, Katayama T, Sato H, Hamaoka-Tamura Y, Saito M, Furuta K, Tanaka S.

(16) Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac diseaseNature communicationsDecember 22, 2023Okura Y, Ikawa-Teranishi Y, Mizoroki A, Takahashi N, Tsushima T, Irie M, Harfuddin Z, Miura-Okuda M, Ito S, Nakamura G, et al.

(17) Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent mannerNature communicationsSeptember 28, 2023Luis TC, Barkas N, Carrelha J, Giustacchini A, Mazzi S, Norfo R, Wu B, Aliouat A, Guerrero JA, Rodriguez-Meira A, et al.

(18) Precision RNAi using synthetic shRNAmir target siteseLifeAugust 8, 2023Hoffmann T, Hörmann A, Corcokovic M, Zmajkovic J, Hinterndorfer M, Salkanovic J, Spreitzer F, Köferle A, Gitschtaler K, Popa A, et al.

(19) Nore1 inhibits age-associated myeloid lineage skewing and clonal hematopoiesis but facilitates termination of emergency (stress) granulopoiesisThe Journal of biological chemistryJuly 1, 2023Williams O, Hu L, Huang W, Patel P, Bartom ET, Bei L, Hjort E, Hijiya C, Eklund EA.

(20) IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophilsCell reportsJune 27, 2023Bénard A, Mittelstädt A, Klösch B, Glanz K, Müller J, Schoen J, Nüse B, Brunner M, Naschberger E, Stürzl M, et al.

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IL-3 Protein

IL-3 Protein

IL-3 Protein

IL-3 Protein

IL-3 Protein

IL-3 Protein from R&D Systems, a Bio-Techne Brand

Description

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (189)

Reviews

IL-3 Protein from R&D Systems, a Bio-Techne Brand

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