Recombinant Mouse Osteopontin/OPN Protein, CF 441-OP-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse Osteopontin/OPN Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $324.00Supplier Page View Company Product Page
Catalog Number441-OP-050/CF
SpeciesMouse
FormatLyophilized from a 0.2 µm filtered solution in PBS
Size50 ug (also 200 ug)
Molecule NameOsteopontin/OPN
NCBI Full Gene Namesecreted phosphoprotein 1
NCBI Gene AliasesBSPI, Apl-1, ETA-1, Opnl, Bsp, Spp-1, Eta, 2AR, BNSP, Opn, Ric, OP
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular WeightObserved: 30 kDa and a 65 kDa doublet, reducing conditions
Theoretical: 31.5 kDa
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Mouse Osteopontin/OPN Protein, CF
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Definition of the contribution of an Osteopontin-producing CD11c(+) microglial subset to Alzheimer's diseaseProceedings of the National Academy of Sciences of the United States of AmericaFebruary 7, 2023Qiu Y, Shen X, Ravid O, Atrakchi D, Rand D, Wight AE, Kim HJ, Liraz-Zaltsman S, Cooper I, Schnaider Beeri M, et al.

(2) Microglia-Derived Spp1 Promotes Pathological Retinal Neovascularization via Activating Endothelial Kit/Akt/mTOR SignalingJournal of personalized medicineJanuary 11, 2023Bai Q, Wang X, Yan H, Wen L, Zhou Z, Ye Y, Jing Y, Niu Y, Wang L, Zhang Z, et al.

(3) Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent MannermBioDecember 20, 2022Chen J, Zeng P, Gong L, Zhang X, Ling Z, Bi K, Shi F, Wang K, Zhang Q, Jiang J, et al.

(4) CD248 Regulates Wnt Signaling in Pericytes to Promote Angiogenesis and Tumor Growth in Lung CancerCancer researchOctober 17, 2022Hong CL, Yu IS, Pai CH, Chen JS, Hsieh MS, Wu HL, Lin SW, Huang HP.

(5) Identification of kidney injury released circulating osteopontin as causal agent of respiratory failureScience advancesFebruary 25, 2022Khamissi FZ, Ning L, Kefaloyianni E, Dun H, Arthanarisami A, Keller A, Atkinson JJ, Li W, Wong B, Dietmann S, et al.

(6) Osteopontin on the Dental Implant Surface Promotes Direct Osteogenesis in OsseointegrationInternational journal of molecular sciencesJanuary 18, 2022Makishi S, Yamazaki T, Ohshima H.

(7) Inducible T-Cell Costimulator Ligand Plays a Dual Role in Melanoma Metastasis upon Binding to Osteopontin or Inducible T-Cell CostimulatorBiomedicinesDecember 27, 2021Raineri D, Cappellano G, Vilardo B, Maione F, Clemente N, Canciani E, Boggio E, Gigliotti CL, Monge C, Dianzani C, et al.

(8) Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic strokeImmunityJuly 13, 2021Shi L, Sun Z, Su W, Xu F, Xie D, Zhang Q, Dai X, Iyer K, Hitchens TK, Foley LM, et al.,Thermo Fisher Scientific,Cat#34-8021-85 Luxol® Fast Blue MBSN,Sigma-Aldrich,Cat#S3382-25G Osteopontin Protein,R&D Systems,Cat#441OP050CF Percoll,GE Healthcare,Cat#17-0891-01 PLX5622,Chemgood,Cat#C-1521 (Z)-4-Hydroxytamoxifen,Sigma-Aldrich,Cat#H7904 Critical

(9) The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in miceNature communicationsMay 18, 2020Yoshida S, Nakagami H, Hayashi H, Ikeda Y, Sun J, Tenma A, Tomioka H, Kawano T, Shimamura M, Morishita R, et al.

(10) Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved OsteopontinJournal of the American Heart AssociationFebruary 4, 2020Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Dunér P, Tønnessen T, Lunde IG, et al.

(11) The effects of macrophages on cardiomyocyte calcium-handling function using in vitro culture modelsPhysiological reportsJuly 1, 2019Hitscherich PG, Xie LH, Del Re D, Lee EJ.

(12) Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblast migration in the mouse brain after strokeStem cell research & therapyJuly 4, 2018Rogall R, Rabenstein M, Vay S, Bach A, Pikhovych A, Baermann J, Hoehn M, Couillard-Despres S, Fink GR, Schroeter M, et al.

(13) Leptin/Osteopontin Axis Regulated Type 2T Helper Cell Response in Allergic Rhinitis with ObesityEBioMedicineJune 1, 2018Zeng Q, Luo X, Han M, Liu W, Li H.

(14) Megakaryocyte and Osteoblast Interactions Modulate Bone Mass and HematopoiesisStem cells and developmentMay 15, 2018Alvarez MB, Xu L, Childress PJ, Maupin KA, Mohamad SF, Chitteti BR, Himes E, Olivos DJ 3rd, Cheng YH, Conway SJ, et al.

(15) Alcohol exposure decreases osteopontin expression during fracture healing and osteopontin-mediated mesenchymal stem cell migration in vitroJournal of orthopaedic surgery and researchApril 27, 2018Natoli RM, Yu H, Meislin MC, Abbasnia P, Roper P, Vuchkovska A, Xiao X, Stock SR, Callaci JJ.

(16) Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitisImmunology and cell biologyApril 1, 2018Zhao G, Hu M, Li C, Lee J, Yuan K, Zhu G, Che C.

(17) Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injuryPLoS geneticsOctober 1, 2017Quattrocelli M, Capote J, Ohiri JC, Warner JL, Vo AH, Earley JU, Hadhazy M, Demonbreun AR, Spencer MJ, McNally EM.

(18) "Osteopontin facilitates West Nile virus neuroinvasion via neutrophil ""Trojan horse"" transport"Scientific reportsJuly 5, 2017Paul AM, Acharya D, Duty L, Thompson EA, Le L, Stokic DS, Leis AA, Bai F.

(19) Early gene activation initiates neuroinflammation prior to VSV neuroinvasion: Impact on antiviral responses and sleepJournal of neuroimmunologyFebruary 15, 2017Ciavarra RP, Lundberg P, Machida M, Ambrozewicz MA, Wellman LL, Breving K, Steel C, Sanford LD.

(20) Intravital Förster resonance energy transfer imaging reveals osteopontin-mediated polymorphonuclear leukocyte activation by tumor cell emboliCancer scienceFebruary 1, 2017Kamioka Y, Takakura K, Sumiyama K, Matsuda M.

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Recombinant Mouse Osteopontin/OPN Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse Osteopontin/OPN Protein, CF from R&D Systems, a Bio-Techne Brand

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