Recombinant Human IL-34 (carrier-free) 577906 from BioLegend

Product Specs
ItemRecombinant Human IL-34 (carrier-free)
CompanyBioLegend
Price $1,026.00Supplier Page View Company Product Page
Catalog Number577906
Size100UG
ApplicationsBA
Gene Nameinterleukin 34
NCBI Gene AliasesC16orf77, IL-34
NCBI Full Gene Nameinterleukin 34
Format0.22 µm filtered protein solution is in 10 mM Sodium Phosphate buffer, 500 mM NaCl, pH 7.4
Molecule NameIL-34
SpeciesHuman

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Fax: 1-877-455-9587

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Website: biolegend.com

(1) Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived modelsbioRxiv : the preprint server for biologyDecember 13, 2025Barr HJ, Depp C, Hingerl M, Nguyen T, Reimertz JM, Connolly E, Patel J, Doman JL, Marsh SE, Stevens B.(Peprotech, cat #AF-300–25), 50ng/mL TGFβ-1 (Peprotech, cat #100–21) and 100ng/mL IL-34 (BioLegend, cat #577906) to the end of the differentiation. Cells were fed with 1mL media every other day. On day 22, floating

(2) Generation of 3D Human iPSC-Derived Multi-Cell Type Neurospheres for Studying Neuron, Astrocyte, and Microglia CrosstalkBio ProtocNovember 5, 2025Stefan Wendt, Christopher Lee, Wenji Cai, Ada J. Lin, Jessica Huang, V. Poon, Xianyuan Xiang, Wei Hong, Brian A. MacVicar, Haakon B. Nygaardaliquots at -20 °C 35. Recombinant human IL-34 (carrier-free) 100 μg (IL-34) (BioLegend, catalog number: 577906); sold at varying concentrations ~1 mg/mL. If above this concentration, adjust by adding dH2O to achieve

(3) Generation of 3D Human iPSC-Derived Multi-Cell Type Neurospheres for Studying Neuron, Astrocyte, and Microglia CrosstalkBIO-PROTOCOLNovember 5, 2025Stefan Wendt, Christopher Lee, Wenji Cai, Ada J. Lin, Jessica Huang, V. Poon, Xianyuan Xiang, Wei Hong, Brian A. MacVicar, Haakon B. Nygaardaliquots at -20 °C 35. Recombinant human IL-34 (carrier-free) 100 μg (IL-34) (BioLegend, catalog number: 577906); sold at varying concentrations ~1 mg/mL. If above this concentration, adjust by adding dH2O to achieve

(4) The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degenerationJ NeuroinflammationOctober 27, 2025Henry Kurniawan, Sarah L. Nickels, Alise Zagare, Elisa Zuccoli, Isabel Rosety, Gemma Gomez-Giro, Enrico Glaab, Jens C. Schwambornβ-Mercaptoethanol (ThermoFisher Scientific, 31350–010) supplemented with 100 ng/ml IL-34 (Biolegend, 577906), and 10 ng/ml GM-CSF (Biolegend, 572905) as described previously [17]. Medium was changed twice weekly.

(5) A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosisJournal of neuroinflammationApril 24, 2025Wendt S, Lin AJ, Ebert SN, Brennan DJ, Cai W, Bai Y, Kong DY, Sorrentino S, Groten CJ, Lee C, et al.USA, 12,604,013) and resuspended in NMM supplemented with 100 ng/mL IL- 34 (BioLegend, San Diego, USA, 577906) and 25 ng/mL TGFβ1 (PeproTech, Cranbury, USA, 100 - 21) and added to well-attached hiNS in 48-well

(6) Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseasesiScienceMarch 17, 2023Hong Y, Dong X, Chang L, Xie C, Chang M, Aguilar JS, Lin J, Lin J, Li QQ.suspension culture plate. The organoids were maintained in NMM supplemented with 100 ng/mL IL34 (BioLegend, Cat# 577906), 5 ng/mL CSF (BioLegend, Cat# 574804), and 50 ng/mL TGF-β (Life Technologies Inc., Cat # PIRP8600). For

(7) Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and ImmunosuppressionCell reportsNovember 17, 2020Rexach JE, Polioudakis D, Yin A, Swarup V, Chang TS, Nguyen T, Sarkar A, Chen L, Huang J, Lin LC, et al.0.055mM beta-mercaptoethanol, 1x N2 supplement (Thermo Fisher, 17502048), 100ng/mL IL-34 (Biolegend, 577906), and 10ng/mL GM-CSF (Biolegend, 766104). Microglia-like cells can be maintained up to 14 days after

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Recombinant Human IL-34 (carrier-free) from BioLegend

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Recombinant Human IL-34 (carrier-free) from BioLegend

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