Recombinant C. difficile Toxin B/TcdB Protein, CF 6246-GT-020 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant C. difficile Toxin B/TcdB Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number6246-GT-020
FormatSupplied as a 0.2 µm filtered solution in Tris and NaCl
SpeciesC. difficile
Size20 ug
Molecule NameToxin B/TcdB
Source/Expression SystemE. coli-derived Recombinant C. difficile Toxin B/TcdB Protein, CF
Molecular WeightObserved: 60-65 kDa, reducing conditions
Theoretical: 64 kDa
ApplicationsEnzyme Activity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Modulation of colonic immunometabolic responses during Clostridioides difficile infection ameliorates disease severity and inflammationScientific reportsSeptember 7, 2023Tubau-Juni N, Bassaganya-Riera J, Leber AJ, Alva SS, Baker R, Hontecillas R.

(2) NLRP3 licenses NLRP11 for inflammasome activation in human macrophagesNature immunologyJune 1, 2022Gangopadhyay A, Devi S, Tenguria S, Carriere J, Nguyen H, Jäger E, Khatri H, Chu LH, Ratsimandresy RA, Dorfleutner A, et al.

(3) Investigation of the adsorption capacity of the enterosorbent Enterosgel for a range of bacterial toxins, bile acids and pharmaceutical drugsScientific reportsApril 4, 2019Howell CA, Mikhalovsky SV, Markaryan EN, Khovanov AV.

(4) Treatment of Clostridium difficile Infection with a Small-Molecule Inhibitor of Toxin UDP-Glucose Hydrolysis ActivityAntimicrobial agents and chemotherapyMay 1, 2018Stroke IL, Letourneau JJ, Miller TE, Xu Y, Pechik I, Savoly DR, Ma L, Sturzenbecker LJ, Sabalski J, Stein PD, et al.

(5) Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's diseaseThe Journal of clinical investigationMay 1, 2018Mao L, Kitani A, Similuk M, Oler AJ, Albenberg L, Kelsen J, Aktay A, Quezado M, Yao M, Montgomery-Recht K, et al.flagellin (tlrl-epstfla-5), PMA (P8139), and MSU (tlrl-msu) were purchased from InvivoGen. TcdB toxin (6246-GT-020) was purchased from R&D Systems. Disuccinimidyl suberate (DSS) crosslinker (S1885) was purchased from

(6) Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDSNature immunologyAugust 1, 2016Park YH, Wood G, Kastner DL, Chae JJ.

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Recombinant C. difficile Toxin B/TcdB Protein, CF from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant C. difficile Toxin B/TcdB Protein, CF from R&D Systems, a Bio-Techne Brand

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