BMP-4 Protein 314-BP-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemBMP-4 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $434.00Supplier Page View Company Product Page
Catalog Number314-BP-010
SpeciesHuman
Molecule NameBMP-4
Size10 ug (also 20 ug, 50 ug, 500 ug, 1 mg)
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
ApplicationsBioactivity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human BMP-4 Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 10 ug (also 20 ug, 50 ug, 500 ug, 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Cranial placode differentiation defect in individuals born without a noseStem Cell ReportsMay 12, 2026Vanitha Venkoba Rao, Xinran Ji, Jasmine Yi Ying Heng, Frederique Magdinier, Bruno Reversade, Shifeng Xuegrown in Essential 6 Medium (E6) (Thermo Fisher, A1516401) supplemented with 5 ng/mL BMP4 (Bio-Techne, 314-BP-010) and 10μM SB431542 (Bio-Techne, 1614). From days 3 to 12, cells were grown in E6 media supplemented

(2) Soluble Notch agonist enables human ameloblast maturation and enamel-like tissue formation for tooth regenerationInt J Oral SciMarch 2, 2026Anjali P. Patni, Rubul Mout, Ammar Alghadeer, Rachel H. Moore, Samera Nademi, Brandon J. Ausk, Philippe Huber, Riya Keshri, Mary Regier, Robert A. Cornell, et al.On day 3 of differentiation 150 pmol/L of monomeric bone morphogenic protein-4 (BMP4) (rndsystems, #314-BP-010) is added daily until day 7. At day 8, the base media is supplemented with 1 μmol/L of BMP-I inhibitor

(3) Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC ‐Cardiomyocytes in the Infarcted Rat HeartMagnetic Resonance in MedicineFebruary 26, 2026Keyu Zhuang, Faisal J. Alibhai, Beiping Qiang, Rocco Romagnuolo, Kyle D. W. Vollett, Bradley K. C. Freeman, M. Juliana Gomez‐Garcia, Tamilla Sadikov Valdman, Tameshwar Ganesh, Yu‐Qing Zhou, et al.monothioglycerol (MTG, Sigma‐Aldrich, M6145), bone morphogenetic protein‐4 (BMP4, 1 ng/mL, R&D Systems, #314‐BP‐010), and ROCK inhibitor Y‐27632 (10 μM, StemCell Technologies). EBs were then treated with a growth factor

(4) Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug TreatmentsAdvanced Healthcare MaterialsDecember 30, 2025Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig(3 mm; Tocris, 4423), 50 µL recombinant human bone morphogenetic protein 4 (10 µg mL−1; R&D systems, 314‐BP‐010), 50 µL retinoic acid (100 µm; Sigma‐Aldrich, R2625). CK/DCI medium: 45 mL cSFM, 5 mL 10× CI, 50 µL

(5) VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartmentProceedings of the National Academy of SciencesDecember 2, 2025Ruben I. Calderon, Nirvay Sah, Molly Huang, Sampada Kallol, Ryan H. Kittle, Walee B. Shaik, Ahmed Abdelbaki, Jennifer N. Chousal, Robert Morey, Tony Bui, et al.S1049) and differentiated in basal media with 10 ng/mL recombinant human BMP4 (R&D Systems, cat. no. 314-BP-010), and 2 μM IWP2 (Selleck Chemicals, cat. no. S7085). At day 4, cells were either collected for analysis

(6) Protocol to quantify protein phosphorylation in mouse extended pluripotent stem cell-derived blastoidsSTAR ProtocolsDecember 1, 2025Tianxia Xiao, Yuxin Luo, Yang Yu(KSOM),Sigma,MR-101 Y-27632,Selleckchem,S1049 rhFGF4,R&D Systems,235-F4 Heparin,Sigma,H3149 A83-01,Selleckchem,S7692 BMP4,R&D Systems,314-BP-010 Phosphate-buffered saline (PBS),Thermo Fisher Scientific,C10010500BT Trypsin-EDTA,Thermo Fisher Scientific,25200056 8

(7) Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of actionThe Journal of experimental medicineNovember 3, 2025Wilhelmsen K, Deshpande A, Tronnes S, Mahanta M, Banicki M, Cochran M, Cowdin S, Fortney K, Hartman G, Hughes RE, et al.onto low-adherent, U-bottom 96-well plates in Essential 8 medium supplemented with 50 ng/ml BMP-4 (314-BP010; R&D Systems) and 10 μM Rock inhibitor. The plates were centrifuged for 3 min at 800 × g, 4°C, and incubated

(8) Human iPSC-derived salivary gland organoids model diabetic salivary gland dysfunctionbioRxivOctober 8, 2025Devon Duron Ehnes, Akira Morishita, Ashish Phal, Hee Yun Jung, Yen Chian Lim, Zachary Foreman, Vincenzo Cirulli, Julie Mathieu, Hannele Ruohola-Bakerand d5, cells are Epicult-C base media supplemented with 400nM SAG and 50ng/mL BMP4 (R&D Systems, #314-BP-010). On d8, cells are fed with Epicult-C base supplemented with 400nM SAG, 5uM CHIR99021 (Selleck Chemical

(9) Establishment of human gastrulating stem cells with the capacity of stable differentiation into multiple gastrulating cell typesCell researchOctober 1, 2025Huang M, Chen M, Yuan G, Cui Y, Shen B, Liu Z, Zhang B, Chen J, Chen D, Qiu S, et al.

(10) Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality controlNature structural & molecular biologyOctober 1, 2025Rodschinka G, Forcelloni S, Kühner FM, Wani S, Riemenschneider H, Edbauer D, Behrens A, Nedialkova DD.

(11) OpenEMMU: A versatile, open-source EdU multiplexing methodology for studying DNA replication and cell cycle dynamicsiScienceSeptember 19, 2025Osvaldo Contreras, Chris Thekkedam, John Zaunders, Ismael Aguirre-MacLennan, Nicholas J. Murray, Anai Gonzalez-Cordero, Richard P. HarveyCMRIi0013-A-6 respectively, 50 ng/mL Activin A (R&D Systems, #338-AC-10), 10 ng/mL BMP4 (R&D Systems, #314-BP-010), 30 ng/mL FGF2 (R&D Systems, #233-FB-025). Three days later (D3), cardiac mesoderm induction started

(12) CUT&TIME captures the history of open chromatin in developing neuronsbioRxiv : the preprint server for biologySeptember 6, 2025Eldred KC, Wooten M, Janssens DH, Hahn J, Neph SJ, Edgerton SJ, Wyatt-Draher G, Sherman SM, Ranchalis JE, Stergachis AB, et al.

(13) Zbtb16 determines the fate plasticity of cardiovascular progenitors through IGF2BP3-mediated mRNA stabilizationCell reportsAugust 26, 2025Wang W, Lian Y, Li J, Wu Y, Li M, Wu Y, Xu R, Zhao X, Kang J, Guo X.

(14) Metastatic small cell lung cancer arises from TP53/RB1-deficient and MYC overproduction hESC-derived PNECsElifeJuly 22, 2025Huanhuan Joyce Chen, Eric E Gardner, Yajas Shah, Kui Zhang, Abhimanyu Thakur, Chen Zhang, Olivier Elemento, Harold Varmus,STEMCELL Technology,07920,– "Chemical compound, drug",Y-27632,R&D Systems,1254,– "Chemical compound, drug",Human BMP4,R&D Systems,314-BP-010,– "Chemical compound, drug",Human bFGF,R&D Systems,233-FB,– "Chemical compound, drug",Human Activin

(15) Formation of malignant, metastatic small cell lung cancers through overproduction of cMYC protein in TP53 and RB1 depleted pulmonary neuroendocrine cells derived from human embryonic stem cellsElifeJuly 22, 2025Huanhuan Joyce Chen, Eric E Gardner, Yajas Shah, Kui Zhang, Abhimanyu Thakur, Chen Zhang, Olivier Elemento, Harold Varmus,STEMCELL Technology,07920,– "Chemical compound, drug",Y-27632,R&D Systems,1254,– "Chemical compound, drug",Human BMP4,R&D Systems,314-BP-010,– "Chemical compound, drug",Human bFGF,R&D Systems,233-FB,– "Chemical compound, drug",Human Activin

(16) Regulation of cortical bone formation by SLIT and NTRK like family member 1iScienceJuly 18, 2025Tomohiko Shirakawa, Tsuyoshi Sato, Kenichi Nagano, Takumi Ito, Moyuri Inoue, Hisako Kaneda, Chihiro Nakatomi, Mitsushiro Nakatomi, Quan Yuan, William N. Addison, et al.Wako,Cat#165-26021 Recombinant Human BMP-2,R&D Systems,Cat#355-BEC Recombinant Human BMP-4,R&D Systems,Cat#314-BP-010 TRIzolTM Reagent,Thermo Fisher Scientific,Cat#15596026 "4′,6-diamidino-2-phenylindole, dihydrochloride

(17) Identification of functional non-coding variants associated with orofacial cleftNature communicationsJuly 16, 2025Kumari P, Friedman RZ, Curtis SW, Pi L, Paraiso K, Visel A, Rhea L, Dunnwald M, Patni AP, Mar D, et al.agonist (Selleckchem, Catalog no. S7779). 150pM of Bone Morphogenic Protein-4 (R&D Systems, Catalog no. 314-BP-010) is continuously added daily starting from day 3 to day 7 of differentiation. At day 8, the media is

(18) IGF2BP1 restricts the induction of human primordial germ cell fate in an m(6)A-dependent mannerCell stem cellJuly 3, 2025Zhang J, Gu Y, Tong L, Feng B, Dong S, Shao Q, Chen Y, Tu H, Wang Z, Wang Y, et al.

(19) Establishment of bovine extraembryonic endoderm stem cells enables efficient blastoid formationCell reportsJune 24, 2025Ming H, Scatolin GN, Ojeda-Rojas OA, Jiang Z.

(20) Development of large-scale gastruloid array to identify aberrant developmental phenotypesAPL BioengJune 10, 2025Ian Jan, Andrew Cearlock, Min Yang, Nancy L. Allbrittonculture medium was replaced with mTeSR Plus containing 50 ng/ml bone morphogenetic protein 4 (BMP4) (#314-BP-010, R&D Systems, Minneapolis, MN) following two gentle rinses with DMEM/F12. The patterned cells were incubated

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BMP-4 Protein

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BMP-4 Protein

BMP-4 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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BMP-4 Protein from R&D Systems, a Bio-Techne Brand

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