Description
Galectin-1 is a member of the beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This protein is an autocrine negative growth factor that regulates cell proliferation. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes, thus Galectin-1 has immunosuppressive and anti-inflammatory properties. Galectin-1 also regulates tumor angiogenesis and is a target for angiostatic cancer therapy. Recombinant human Galectin-1 was expressed in E.coli and purified by using conventional chromatography