Recombinant Human BMP-8a Protein 1073-BP-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human BMP-8a Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $453.00Supplier Page View Company Product Page
Catalog Number1073-BP-010
Size10 ug
ApplicationsBinding Activity
FormatLyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein
Purity>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Molecular Weight15.8 kDa (monomer)
Conjugate/TagUnconjugated
SpeciesHuman
Molecule NameBMP-8a
Source/Expression SystemE. coli-derived Recombinant Human BMP-8a Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namebone morphogenetic protein 8a
NCBI Gene AliasesOP-2

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competenceCell reportsJanuary 31, 2023Luo Q, Pui HP, Chen J, Yu L, Jannig PR, Pei Y, Zhao L, Chen X, Petropoulos S, Ruas JL, et al.FC010 Recombinant Human BMP4,R&D Systems,Cat# 314-BP-050 Recombinant Human BMP8a,R&D Systems,Cat# 1073-BP-010 Recombinant Mouse SCF,R&D Systems,Cat# 455-MC-010 Recombinant Mouse EGF,R&D Systems,Cat# 2028-EG-200 ,, Critical

(2) Loss of Resf1 reduces the efficiency of embryonic stem cell self-renewal and germline entryLife science allianceDecember 1, 2021Vojtek M, Chambers I.Invitrogen]) with freshly added 50 ng/ml Bmp4 (Cat. no. 314-BP-010; R&D Systems), 50 ng/ml Bmp8a (Cat. no. 1073-BP-010; R&D Systems), 2 ng/ml SCF (Cat. no. 455-MC-010; R&D Systems), 500 ng/ml EGF (Cat. no. 2028-EG-010;

(3) Formative pluripotent stem cells show features of epiblast cells poised for gastrulationCell researchMay 1, 2021Wang X, Xiang Y, Yu Y, Wang R, Zhang Y, Xu Q, Sun H, Zhao ZA, Jiang X, Wang X, et al.Systems, Cat# 315-27), 100 ng/mL SCF (R&D Systems, Cat# 455-MC-010), 500 ng/mL BMP8a (R&D Systems, Cat# 1073-BP-010), 50 ng/mL EGF (R&D Systems, Cat# 2028-EG), and 1000 units/mL hLIF. Neural precursor induction of mESCs

(4) Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouseNature communicationsMarch 6, 2019Senft AD, Bikoff EK, Robertson EJ, Costello I.

(5) Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage PrimingCell reportsAugust 21, 2018Senft AD, Costello I, King HW, Mould AW, Bikoff EK, Robertson EJ.

(6) In vitro differentiation of human embryonic stem cells into ovarian follicle-like cellsNature communicationsJune 12, 2017Jung D, Xiong J, Ye M, Qin X, Li L, Cheng S, Luo M, Peng J, Dong J, Tang F, et al.

(7) Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell SpecificationMolecular cellFebruary 2, 2017Hu D, Gao X, Cao K, Morgan MA, Mas G, Smith ER, Volk AG, Bartom ET, Crispino JD, Di Croce L, et al.2-Mercaptoethanol,ThermoFisher,Cat# 21985023 BMP-4,R&D Systems,Cat# 314-BP-010 BMP8a,R&D Systems,Cat# 1073-BP-010 SCF,R&D Systems,Cat# 455-MC-010 EGF,R&D Systems,Cat# 2028-EG-200 Protein A/G PLUS-Agarose,Santa Cruz,Cat#

(8) Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidiesScientific reportsSeptember 22, 2014Dominguez AA, Chiang HR, Sukhwani M, Orwig KE, Reijo Pera RA.

(9) Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6PloS oneJanuary 1, 2014Sharma A, Huard C, Vernochet C, Ziemek D, Knowlton KM, Tyminski E, Paradis T, Zhang Y, Jones JE, von Schack D, et al.brown fat. Materials and Methods Reagents Recombinant human BMPs: BMP6 (507-BP-020), BMP7 (354-BP-010) and BMP8 (1073-BP-010) were purchased from R&D Systems. The following antibodies were purchased from Santa Cruz Biotechnology:

(10) Generation of human induced pluripotent stem cells using epigenetic regulators reveals a germ cell-like identity in partially reprogrammed coloniesPloS oneJanuary 1, 2013Goyal A, Chavez SL, Reijo Pera RA.

(11) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitorsNatureJuly 26, 2012Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, et al.

(12) Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cellsJournal of assisted reproduction and geneticsMay 1, 2011Geens M, Sermon KD, Van de Velde H, Tournaye H.

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Recombinant Human BMP-8a Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human BMP-8a Protein from R&D Systems, a Bio-Techne Brand

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