NEXN ELISA kits are immunoassay tools for the measurement of the protein nexilin F-actin binding protein, which is encoded by the NEXN gene in humans. Functionally, this protein is known to be involved in regulating cell migration through association with the actin cytoskeleton. The canonical protein structure is reported to have an amino acid sequence of 675 residues and a mass of 80.7 kDa. It is known to be localized in the cytoplasm and is found to be highly expressed in heart and skeletal muscle, and at lower levels in placenta, lung, liver and pancreas. As many as 4 protein isoforms have been reported. The NEXN gene has been associated with the disease, Cardiomyopathy. Other alias names for this target include nexilin.
The detection range for different NEXN ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.