GGCX ELISA kits are immunoassay tools for the measurement of the protein gamma-glutamyl carboxylase, which is encoded by the GGCX gene in humans. Functionally, this protein is known to mediate the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. The canonical protein structure is reported to have an amino acid length of 758 residues, a mass of 87.6 kDa, and is a member of the Vitamin K-dependent gamma-carboxylase protein family. It is known to be localized in the ER. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The GGCX gene has been associated with the disease, Combined deficiency of vitamin K-dependent clotting factors. Other alias names for this target include vitamin K-dependent gamma-carboxylase, peptidyl-glutamate 4-carboxylase, and VKCFD1.
The detection range for different GGCX ELISA kits can vary, with some assays measuring target concentrations as low as 78 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.