The following Spindlin 1 ELISA kits are useful research tools for the measurement of spindlin 1 in biological samples. In humans this protein is encoded by the SPIN1 gene. This protein is reported to be a chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2. The canonical protein structure is reported to have an amino acid length of 262 residues, a mass of 29.6 kDa, and is a member of the SPIN/STSY protein family. Its subcellular location is known to be in the nucleus. In addition, it is reported to be highly expressed in ovarian cancer tissues. In certain instances, it is also post-translationally phosphorylated. This protein may also be known as TDRD24, ovarian cancer-related protein, and SPIN.
There are spindlin 1 ELISA kits that can detect a target at concentrations as low as 15 ng/L and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.