Anti-NTG antibodies enable researchers to detect and measure the NTG antigen in biological samples. This target is a reported synonym of the OPA1 gene, which encodes OPA1 mitochondrial dynamin like GTPase. This protein is known to function in the apoptotic pathway, among other biological roles. The human version of NTG has a canonical amino acid length of 960 residues and a protein mass of 111.6 kilodaltons, although 6 isoforms have been identified. It is reported to be localized in the mitochondria of cells and widely expressed in many tissue types. NTG is a member of the Dynamin/Fzo/YdjA protein family.