Anti-PVALB antibodies are used in the immunodetection of the protein parvalbumin. In humans, the canonical protein has a reported length of 110 amino acid residues and a mass of 12.1 kDa. It is notably expressed in the parathyroid gland, kidney, cerebral cortex, and cerebellum. It is a member of the Parvalbumin protein family. The PVALB marker can be used to identify Cerebral Cortex MGE Interneurons and Thalamic Excitatory Neurons.* Synonyms for this target antigen include D22S749 and parvalbumin alpha. PVALB gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 1200 citations in the literature describe the use of PVALB antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4