Anti-DYNC2H1 antibodies are used in the immunodetection of the protein dynein cytoplasmic 2 heavy chain 1. In humans, the canonical protein has a reported length of 4307 amino acid residues and a mass of 492.6 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Dynein heavy chain protein family, DYNC2H1 is believed to function as a a motor for intraflagellar retrograde transport. The DYNC2H1 gene has been associated with the disease, Short-rib thoracic dysplasia 3 with or without polydactyly. Synonyms for this target antigen include dynein cytoplasmic heavy chain 2, dynein heavy chain 11, dynein heavy chain, isotype 1B, dynein, cytoplasmic, heavy polypeptide 2, and cytoplasmic dynein 2 heavy chain 1. DYNC2H1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some DYNC2H1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.