Anti-ATXN3 antibodies are used in the immunodetection of the protein ataxin 3. In humans, the canonical protein has a reported length of 361 amino acid residues and a mass of 41.3 kDa. Its subcellular localization is in the nucleus. Up to 5 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. ATXN3 is known to be a deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Synonyms for this target antigen include ATX3, JOS, MJD, MJD1, SCA3, Machado-Joseph disease protein 1, josephin, and AT3. ATXN3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ATXN3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.