Anti-CDP-L-ribitol pyrophosphorylase A antibodies are used for the immunodetection of the protein encoded by the CRPPA gene. In humans, the canonical protein has a reported length of 451 amino acid residues and a mass of 49.9 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is widely expressed across many tissue types. A member of the IspD/TarI cytidylyltransferase protein family, it is known to be involved with axon guidance. The gene encoding this protein is implicated in Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies. Other names for this target antigen include 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase homolog, isoprenoid synthase domain containing, and D-ribitol-5-phosphate cytidylyltransferase. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.