Anti-PTOV1 extended AT-hook containing adaptor protein antibodies are used for the immunodetection of the protein encoded by the PTOV1 gene. In humans, the canonical protein has a reported length of 416 amino acid residues and a mass of 46.9 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be expressed in the brain, heart, kidney, liver, placenta, skeletal muscle and small intestine. A member of the Mediator complex subunit 25 protein family, it is believed to activate transcription. Post-translational modifications have been described, including ubiquitination. Other names for this target antigen include prostate tumor-overexpressed gene 1 protein, activator interaction domain-containing protein 2, prostate tumor overexpressed 1, and ACID2. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species.