Anti-acyl-CoA oxidase 1 antibodies are used for the immunodetection of the protein encoded by the ACOX1 gene. In humans, the canonical protein has a reported length of 660 amino acid residues and a mass of 74.4 kDa. Its subcellular localization is in the peroxisomes. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. A member of the Acyl-CoA oxidase protein family, it is reported to be involved in initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Other names for this target antigen include AOX, MITCH, PALMCOX, SCOX, peroxisomal acyl-coenzyme A oxidase 1, and ACOX. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of acyl-CoA oxidase 1 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, and Immunofluorescence are also common applications.