Anti-TUB antibodies are used in the immunodetection of the protein TUB bipartite transcription factor. In humans, the canonical protein has a reported length of 506 amino acid residues and a mass of 55.7 kDa. Its subcellular localization is in the cell membrane, nucleus, cytoplasm, and is secreted. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the TUB protein family, tub is reported to function in signal transduction from heterotrimeric G protein-coupled receptors. The TUB gene has been associated with the disease, Retinal dystrophy and obesity. Synonyms for this target antigen include rd5, tubby protein homolog, tubby bipartite transcription factor, tubby homolog, tubby homologue, and RDOB. TUB gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some tub antibodies may have been used in research and have associated citations. Western Blot and Immunohistochemistry are common applications for these antibodies.