Custom Oligo Synthesis

Custom Oligo Synthesis Custom oligo synthesis services are available from a number of companies for various applications in molecular biology. Genomic research techniques continue to expand at an extraordinary rate, underlining the need for high-quality, rapid, and economical oligonucleotides. These DNA and RNA oligos can include sequencing primers, probes, antisense oligos, siRNA, barcodes, and CRISPR RNA. Entire genomes can now be built directly from oligonucleotides while maintaining very high fidelity. As an oligo synthesis services customer, a gene synthesis error rate that is as low as possible is at the top of the list. Pay careful attention to the modification ranges, synthesis scales, and purity grades offered, since this is a continuously evolving technology area. Submit a quote or visit the oligo synthesis company page for more information.

Custom Oligo Synthesis

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Sponsored Products

Clonal Genes

Clonal Genes

Twist Bioscience

  • Description:
    We offer both Clonal Genes and Gene Fragments for your research needs. Clonal Genes are synthesized DNA cloned into a plasmid vector and NGS sequence verified. Gene Fragments are linear synthesized DNA sequences for direct cloning or larger gene ...
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Oligo Pools

Oligo Pools

Twist Bioscience

  • Description:
    Oligo Length: Up to 300 nt
    Oligo Pool Size: Minimum of 2,000 sequences with no maximum
    Yield: >0.2 fmol for each oligo
    Price: Industry leading pricing
    Turnaround Time: Starting from 5 business days
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Design and Synthesis of Oligo Pool for Barcode library
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Design and Synthesis of Oligo Pool for CRISPR sgRNA library
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Design and Synthesis of Oligo Pool for shRNA library
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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DNA Design

DNA Design

InVivo BioTech

  • Description:
    To reach ideal production rates in eukaryotic or prokaryotic expression systems, it is highly recommended to optimize DNA sequences depending on the specific project requirements. In this regard, InVivo offers a range of different DNA design services...
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Large-scale DNA preparation
  • Description:
    Transient gene expression in mammalian cells requires large amounts of high-quality plasmid DNA. As commercially available kits exclusively use single-use columns and have a limited capacity of only 10 mg, InVivo established a proprietary procedure ...
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Alt-R&#8482; HDR Donor Oligos

Alt-R™ HDR Donor Oligos

Integrated DNA Technologies

  • Description:
    Our proprietary synthesis process delivers HDR-ready oligos of the highest quality, up to 200 bases. Alt-R HDR Donor Oligos are available in tube or plate formats.

    • Ideal for introducing point mutations or short insertions
    • Industry-leading HDR rates
    • ...
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Antisense oligonucleotides

Antisense oligonucleotides

Integrated DNA Technologies

  • Description:
    Antisense oligonucleotides (ASOs) are DNA oligos, typically 15–25 bases long, designed in antisense orientation to the RNA of interest. Hybridization of the ASO to the target RNA mediates RNase H cleavage of the RNA, which can inhibit the ...
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Large scale synthesis

Large scale synthesis

Integrated DNA Technologies

  • Description:
    You can acquire milligram to gram quantities of pure nucleic acids, including aptamers, ribozymes, miRNAs and siRNAs, next generation sequencing adapters, PCR primers, and dual-labeled probes. Obtain high purity DNA and RNA oligos in bulk quantities.
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MonkeyPox qPCR Primers/Probes

MonkeyPox qPCR Primers/Probes

Integrated DNA Technologies

  • Description:
    Primers and probes for MonkeyPox research. Pre-designed and custom primer/probe sets for monkeypox research
OEM services

OEM services

Integrated DNA Technologies

  • Description:
    Using IDT as a third-party OEM supplier gives you access to our entire catalog of genomics products, as well as a full-range of custom services. Our innovative synthesis technologies, manufacturing capabilities, and technical expertise are available ...
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OligoAnalyzer&#8482; 3.1

OligoAnalyzer™ 3.1

Integrated DNA Technologies

  • Description:
    The complementary sequence to the entered oligonucleotide, which is shown in 5' to 3' orientation and in DNA format. Modifications are ignored when the complementary base is determined. However, for modifications that are native base analogs,...
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PrimeTime&#8482; qPCR Probes

PrimeTime™ qPCR Probes

Integrated DNA Technologies

  • Description:
    Select from a broad catalog of synthesis scales, delivery formats, and reporter dye–quencher combinations. PrimeTime qPCR Probes are 5′ nuclease probes that include a fluorescent reporter dye and one or two quencher dye(s).
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PrimerQuest&#8482; Tool

PrimerQuest™ Tool

Integrated DNA Technologies

  • Description:
    qPCR assay design tool. Design primers to your sequence of interest
SameDay&#8482; Oligo Service

SameDay™ Oligo Service

Integrated DNA Technologies

  • Description:
    Specifications:
    • Order online by 11:00 GMT
    • SameDay® priority shipping for delivery by 10:30 GMT on second business day
    • 2-OD minimum guarantee (sufficient for > 250 PCR reactions)
    • 15-45 bases
    • Shipped lyophilized in tubes
    • Deprotected ...
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Combinatorial Variant Libraries
  • Description:
    Twist Bioscience’s unique capability to synthesize very large numbers of high quality oligos with our massively parallel silicon-based DNA synthesis platform, combined with our well established molecular biology expertise, allow the controlled ...
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GPCR Libraries

GPCR Libraries

Twist Bioscience

  • Description:
    > 100,000 Different GPCR Binding Motifs
    • With over 100,000 different GPCR binding motifs, unlock the discovery of antibodies to this difficult-to-target class.
    GPCRS ARE HARD-TO-DRUG
    • 30-50% of current drug targets are GPCRs but there are only 2 FDA ...
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Gene Fragments

Gene Fragments

Twist Bioscience

  • Description:
    • dsDNA
    • 0.3 – 1.8 kb
    • 100 ng – 1 µg per fragment
    • 6 to 9 business day turnaround time
    • 1:3000 average error rate
    No Order Limit
Single-Domain Antibody Libraries
  • Description:
    Twist uses four novel VHH methods that combine synthetic and natural approaches to maximize diversity, creating highquality VHH libraries for use against any protein target. These proprietary, naïve single chain domain libraries are ideal for ...
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Site Saturation Variant Libraries
  • Description:
    Twist Bioscience Site Saturation Variant Libraries leverage massively parallel oligonucleotide synthesis using a silicon-based DNA synthesis platform and extensive molecular biology expertise to systematically and precisely construct variant ...
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Oligonucleotide Synthesis Service
  • Description:
    The oligos have been applied in almost all fields of molecular biology, and have become the top choice for researchers. Creative Biogene provides a full spectrum of high quality specialty Oligonucleotide Synthesis Service that range from oligo ...
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GeneArt Protein Expression & Purification Services
  • Description:
    GeneArt Protein Expression and Purification Services are designed to expand your capacity and expedite your protein and antibody discovery workflow. We’ve combined our R&D breakthroughs in gene synthesis, sequence optimization, and mammalian ...
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