Manipulating the characteristics of the antibody-antigen interaction has proven a useful tool within research. This is seen in immunochemical techniques as well as antibody uses in diagnostic and therapeutic applications. Antiserum from an immunized animal can be used directly for certain applications. However, most often some form of antibody purification is required to obtain an antibody probe that is effective for multiple types of detection methods. Antibody purification kits make the purifying process faster and easier. Kits often include pre-packed centrifugal spin columns to avoid traditional gravity flow methods that are time consuming and require more attention. Choose a kit that is species optimized, as well as compatible with your starting material whether it tissue culture supernatant, serum, or ascites fluid.