The FDA Modernization Act encourages looking into physiologically relevant cellular platforms that can minimize the use of animals for drug development and clinical testing. It also implies that these models have to adhere to certain quality control and performance standards to deliver results that are accurate and reproducible.
This Bench Tips webinar brings together a group of post-doctoral scholars from prominent labs to discuss how 3D cellular models can be generated and utilized to fill this need. The speakers will give short presentations to share their knowledge and expertise on this topic. The talks will be followed by a Q&A session where attendees can ask questions and discuss challenges they may be facing when using 3D cell cultures.
You will learn about:
- Designing 3D models that accurately recapitulate the disease phenotype
- Understanding the advantages and limitations of different types of 3D cell models and co-cultures
- Automating and applying high-throughput 3D cultures for drug and safety screening
- Organoids as a model to study the influence of pregnancy on breast cancer progression
- 3D pancreatic spheroids for studying cancer cell invasion and immune-tumor interactions
- 3D culture methods for tuning extracellular matrix stiffness and architecture