I-BET 151 dihydrochloride from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemI-BET 151 dihydrochloride
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4650/10
Quantity10 mg (also 50 mg)
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.98
Molecular Weight488.37
Molecule Name7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
FormulaC₂₃H₂₁N₅O₃.2HCl
StorageStore at -20°C

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancerMolecular cancerMay 12, 2023Ortiz-Barahona V, Soler M, Davalos V, García-Prieto CA, Janin M, Setien F, Fernández-Rebollo I, Bech-Serra JJ, De La Torre C, Guil S, et al.

(2) BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and ReplicationSSRN Electronic JournalMarch 30, 2022Akhil Bowry, Ann Liza Piberger, Eva Petermannanti-bACTIN Cell Signaling Cat# 4967, RRID:AB_330288 (+)-JQ1 Tocris 4499/10 I-BET151 Tocris 4650/10 AZ20 Tocris 5198/10 Olaparib Selleckchem S1060 Triptolide Tocris 3253/1 DRB Sigma D1916 alpha-Amanitin Sigma A2263 Hydroxyurea Sigma H8627 Click-iT RNA Alexa Fluor 594 Imaging Kit

(3) CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell modelsScientific reportsMarch 24, 2020Rathore A, Iketani S, Wang P, Jia M, Sahi V, Ho DD.

(4) β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprogramingPLoS geneticsDecember 1, 2018Xie X, Jankauskas R, Mazari AMA, Drou N, Percipalle P.

(5) BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and ReplicationCell reportsNovember 20, 2018Bowry A, Piberger AL, Rojas P, Saponaro M, Petermann E.

(6) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal FunctionMolecular cellMay 18, 2017Sakamaki JI, Wilkinson S, Hahn M, Tasdemir N, O'Prey J, Clark W, Hedley A, Nixon C, Long JS, New M, et al.

(7) Reprogramming by De-bookmarking the Somatic Transcriptional Program through Targeting of BET BromodomainsCell reportsSeptember 20, 2016Shao Z, Yao C, Khodadadi-Jamayran A, Xu W, Townes TM, Crowley MR, Hu K.

(8) GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1Scientific reportsMarch 25, 2015Kumar K, Raza SS, Knab LM, Chow CR, Kwok B, Bentrem DJ, Popovic R, Ebine K, Licht JD, Munshi HG.

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