JC-1 from MedChemExpress

Product Specs
ItemJC-1
CompanyMedChemExpress
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberHY-15534
Quantity2 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.0%
TypeChemical
Molecular Weight652.23
FormulaC₂₅H₂₇Cl₄IN₄
Research AreaOthers

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(1) A secreted form of chorismate mutase (Rv1885c) in Mycobacterium bovis BCG contributes to pathogenesis by inhibiting mitochondria-mediated apoptotic cell death of macrophagesJ Biomed SciDecember 18, 2023Mi-Hyun Lee, Hye Lin Kim, Hyejun Seo, Sangkwon Jung, Bum-Joon Kimusing a TMRE-Mitochondrial Membrane Potential Assay Kit (Abcam, ab113852) and JC-1 (MedChemExpress, HY-15534). The FCCP positive control was prepared by adding 20 µM FCCP for 10 min prior to TMRE staining and

(2) Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial homeostasisPflügers Archiv - European Journal of PhysiologyOctober 1, 2023Fatma H. Rizk, Amira A. El Saadany, Marwa Mohamed Atef, Rania Nagi Abd-Ellatif, Dina M. El-Guindy, Muhammad T. Abdel Ghafar, Marwa M. Shalaby, Yasser Mostafa Hafez, Shaimaa Samir Amin Mashal, Eman H. Basha, et al.using methods of Maity et al. [28] and Guha et al. [15] using the cationic carbocyanine dye (JC-1) (HY-15534) (MedChemExpress, New Jersey, USA). In brief, 20 µg of freshly prepared isolated mitochondria were incubated

(3) BCR-ABL triggers a glucose-dependent survival program during leukemogenesis through the suppression of TXNIPCell Death & DiseaseApril 24, 2023Lin Feng, Ruxin Ding, Xuan Qu, Yuanchun Li, Tong Shen, Lei Wang, Ruikai Li, Juan Zhang, Yi Ru, Xin Bu, et al.mass, K562G and K562R cells with or without TXNIP knockdown were stained with the JC-1 reagent (2 μM, #HY-15534, MedChemExpress) and MitoTracker Green (0.1 μM, #HY-135056, MedChemExpress) at 37 °C for 30 min, respectively.

(4) Lipoxin A4 attenuated dexamethasone-induced muscle atrophy via activation of PGC-1α/Nrf2/TFAM pathwayJournal of Physiology and BiochemistryFebruary 1, 2023Fatma H. Rizk, Nema A. Soliman, Shaimaa M. Kashef, Amira A. Elsaadanymeasured as described by Madi et al. [21] and Guha et al. [7] using the cationic carbocyanine dye (JC-1) (HY-15534) (MedChemExpress, New Jersey, USA). In brief, freshly prepared mitochondria (20 µg) isolated from gastrocnemius muscle

(5) O-GlcNAcylation is crucial for sympathetic neuron development, maintenance, functionality and contributes to peripheral neuropathyFrontiers in neuroscienceJanuary 1, 2023Wu HF, Huang CW, Art J, Liu HX, Hart GW, Zeltner N.520 nm emission. Mitochondrial membrane potential Live symN labeling using JC-1 (MedChemExpress, HY-15534) was performed according to manufacturer’s instruction. Briefly, symNs were incubated with 2 μM JC-1

(6) TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagyTheranosticsJanuary 1, 2023Yu B, Jin L, Yao X, Zhang Y, Zhang G, Wang F, Su X, Fang Q, Xiao L, Yang Y, et al.of mitochondrial membrane potential (MMP) The MMP was determined by JC-1 staining (MedChemExpress, HY-15534) following manufacturer's instructions. Briefly, cells were incubated with 2 μM JC-1 for 20 min at 37°C

(7) Cysteine dioxygenase 1 attenuates the proliferation via inducing oxidative stress and integrated stress response in gastric cancer cellsCell death discoveryDecember 16, 2022Ma G, Zhao Z, Qu Y, Cai F, Liu S, Liang H, Zhang R, Deng J.(ab184909) was purchased from Abcam (Cambridge, England). Puromycin dihydrochloride (HY-B1743A), JC-1 (HY-15534), antioxidant compound library (HY-L037), Engeletin (HY-N0436), ISRIB (HY-12495), and Cell Counting

(8) Single Cell Effects of Photobiomodulation on Mitochondrial Membrane Potential and Reactive Oxygen Species Production in Human Adipose Mesenchymal Stem CellsCellsMarch 11, 2022Li-Chern Pan, Nguyen-Le-Thanh Hang, Mamadi M.S Colley, Jungshan Chang, Yu-Cheng Hsiao, Long-Sheng Lu, Bing-Sian Li, Cheng-Jen Chang, Tzu-Sen Yangsolution, H2DCFDA was diluted in Dimethyl sulfoxide (DMSO, MedChemExpress, Monmouth Junction, NJ, USA, HY-15534) and then further diluted before use. Adherent cells (Human Adipose Stem Cells, ADSC) in a flow chamber

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JC-1 from MedChemExpress

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