VKORC1 ELISA kits are immunoassay tools for the measurement of the protein vitamin K epoxide reductase complex subunit 1, which is encoded by the VKORC1 gene in humans. Functionally, this protein is known to be involved in vitamin K metabolism. The canonical protein structure is reported to have an amino acid length of 163 residues, a mass of 18.2 kDa, and is a member of the VKOR protein family. It is known to be localized in the ER and is reported be expressed at highest levels in fetal and adult liver, followed by fetal heart, kidney, and lung, adult heart, and pancreas. As many as 3 protein isoforms have been reported. The VKORC1 gene has been associated with the disease, Combined deficiency of vitamin K-dependent clotting factors. Other alias names for this target include vitamin K dependent clotting factors deficiency 2, vitamin K1 2,3-epoxide reductase subunit 1, vitamin K1 epoxide reductase (warfarin-sensitive), and phylloquinone epoxide reductase.
Some VKORC1 ELISA kits can detect targets at levels as low as 15 ng/L and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.