The following neuronal guanine nucleotide exchange factor ELISA kits are useful research tools for the measurement of neuronal guanine nucleotide exchange factor in biological samples. In humans this protein is encoded by the NGEF gene. This protein is known to act as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. The canonical protein structure is reported to have an amino acid sequence of 710 residues and a mass of 82.5 kDa. Its subcellular location is known to be in the cytoplasm. In addition, it is reported to be highly expressed in the brain specifically in caudate nucleus and to a lower extent in amygdala and hippocampus. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. This protein may also be known as EPHEXIN, ephexin-1, eph-interacting exchange protein, ephexin1, and ARHGEF27.
The detection range for different neuronal guanine nucleotide exchange factor ELISA kits can vary, with some assays measuring target concentrations as low as 78 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.