The Rho guanine nucleotide exchange factor (GEF) 4 ELISA kits listed below utilize specific antibodies for the plate-based assay of Rho guanine nucleotide exchange factor (GEF) 4 in various samples. Rho guanine nucleotide exchange factor (GEF) 4 is another term for the ARHGEF4 gene, which encodes the protein, Rho guanine nucleotide exchange factor 4 in humans. It has been reported that Rho guanine nucleotide exchange factor (GEF) 4 plays a role in intracellular signal transduction and GPCR signaling pathways, among other functions. Structurally, the ARHGEF4 protein is 690 amino acid residues in length and 79.1 kilodaltons in mass. However, as many as 3 protein isoforms have been identified. It is localized to the membrane and cytoplasm of the cell. In terms of tissue specificity, it is notably expressed at high levels in the brain, skeletal muscle and testis and at low levels in the kidney, lung, small intestine, ovary and prostate. Other names for this target antigen include ASEF, ASEF, and ASEF1.
The detection range for different Rho guanine nucleotide exchange factor (GEF) 4 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.