ITM2B ELISA kits are immunoassay tools for the measurement of the protein, integral membrane protein 2B, which is encoded by the ITM2B gene in humans. Functionally, this protein is reported to play a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. The canonical protein structure is reported to have an amino acid length of 266 residues, a mass of 30.3 kDa, and is a member of the ITM2 protein family. It is known to be localized in the golgi and cell membrane and is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated and cleaved. The ITM2B gene has been associated with the disease, Cerebral amyloid angiopathy. Other alias names for this target include BRI, BRI2, BRICD2B, E25B, E3-16, FBD, RDGCA, and ABRI.