COCH ELISA kits are immunoassay tools for the measurement of the protein cochlin, which is encoded by the COCH gene in humans. Functionally, this protein is reported to play a role in in the control of cell shape and motility in the trabecular meshwork. The canonical protein structure is reported to have an amino acid sequence of 550 residues and a mass of 59.5 kDa. It is known to be localized in the extracellular matrix and is secreted and is reported to be expressed in inner ear structures; the cochlea and the vestibule. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and cleaved. The COCH gene has been associated with the disease, Deafness. Other alias names for this target include COCH5B2, DFNA9, DFNB110, coagulation factor C homolog, cochlin (Limulus polyphemus), and COCH-5B2.
The detection range for different COCH ELISA kits can vary, with some assays measuring target concentrations as low as 31.2 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.