PLSCR1 ELISA kits are immunoassay tools for the measurement of the protein phospholipid scramblase 1, which is encoded by the PLSCR1 gene in humans. Functionally, this protein is known to catalyze calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface. The canonical protein structure is reported to have an amino acid length of 318 residues, a mass of 35 kDa, and is a member of the Phospholipid scramblase protein family. It is known to be localized in the cell membrane, nucleus, and cytoplasm and is reported to be expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally palmitoylated and phosphorylated. Other alias names for this target include PL scramblase 1, ca(2+)-dependent phospholipid scramblase 1, erythrocyte phospholipid scramblase, mg(2+)-dependent nuclease, and MMTRA1B.
The detection range for different PLSCR1 ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.