IDE ELISA kits are immunoassay tools for the measurement of the protein insulin degrading enzyme, which is encoded by the IDE gene in humans. Functionally, this protein is reported to play a role in in the cellular breakdown of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. The canonical protein structure is reported to have an amino acid length of 1019 residues, a mass of 118 kDa, and is a member of the Peptidase M16 protein family. It is known to be localized in the cell membrane, cytoplasm, and is secreted and is notably expressed in the brain and in cerebrospinal fluid. As many as 2 protein isoforms have been reported. Other alias names for this target include Abeta-degrading protease, insulin protease, insulinase, and INSULYSIN.
The detection range for different IDE ELISA kits can vary, with some assays measuring target concentrations as low as 3.12 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.