The following deoxyuridine triphosphatase ELISA kits are useful research tools for the measurement of deoxyuridine triphosphatase in biological samples. In humans this protein is encoded by the DUT gene. This protein is known to catalyze the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation into DNA and at the same time provides dUMP, the substrate for de novo thymidylate biosynthesis. The canonical protein structure is reported to have an amino acid length of 252 residues, a mass of 26.6 kDa, and is a member of the DUTPase protein family. Its subcellular location is known to be in the nucleus and mitochondria. As many as 2 protein isoforms have been reported. In certain instances, it is also post-translationally phosphorylated. The gene encoding this protein has been associated with the disease, Bone marrow failure and diabetes mellitus syndrome. This protein may also be known as dUTPase, deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, dUTP diphosphatase, dUTP nucleotidohydrolase, dUTP pyrophosphatase, and BMFDMS.
Some deoxyuridine triphosphatase ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 10 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.