TWNK ELISA kits are immunoassay tools for the measurement of the protein twinkle mtDNA helicase, which is encoded by the TWNK gene in humans. Functionally, this protein is known to be a mitochondrial helicase involved in mtDNA replication and repair. The canonical protein structure is reported to have an amino acid sequence of 684 residues and a mass of 77.2 kDa. It is known to be localized in the mitochondria. As many as 3 protein isoforms have been reported. The TWNK gene has been associated with the disease, Progressive external ophthalmoplegia with mitochondrial DNA deletions. Other alias names for this target include T7 helicase-related protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, progressive external ophthalmoplegia 1 protein, and T7 gp4-like protein with intramitochondrial nucleoid localization. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.