POLR1C ELISA kits are immunoassay tools for the measurement of the protein RNA polymerase I and III subunit C, which is encoded by the POLR1C gene in humans. Functionally, this protein is reported to play a role in in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. The canonical protein structure is reported to have an amino acid sequence of 346 residues and a mass of 39.3 kDa. It is known to be localized in the nucleus. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The POLR1C gene has been associated with the disease, Treacher Collins syndrome. Other alias names for this target include HLD11, RPA39, RPA40, RPA5, RPAC1, RPC40, TCS3, and AC40.
Some POLR1C ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.