IRGM ELISA kits are immunoassay tools for the measurement of the protein immunity related GTPase M, which is encoded by the IRGM gene in humans. Functionally, this protein is reported to be an immunity-related GTPase that plays important roles in innate immunity and inflammatory response. The canonical protein structure is reported to have an amino acid length of 181 residues, a mass of 20.1 kDa, and is a member of the IRG protein family. It is known to be localized in the cytoplasmic vesicles, mitochondria, golgi, lysosomes, and cell membrane and is widely expressed across many tissue types. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated. The IRGM gene has been associated with the disease, Inflammatory bowel disease. Other alias names for this target include LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47-like protein, immunity-related GTPase family, M1, interferon-inducible protein 1, and immunity-related GTPase family M protein.
The detection range for different IRGM ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.