KIDINS220 ELISA kits are immunoassay tools for the measurement of the protein kinase D interacting substrate 220, which is encoded by the KIDINS220 gene in humans. Functionally, this protein is reported to promote a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. The canonical protein structure is reported to have an amino acid sequence of 1771 residues and a mass of 196.5 kDa. It is known to be localized in the membrane and is notably expressed in developing and adult neural tissues as well as neuroendocrine cells and dendritic cells. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The KIDINS220 gene has been associated with the disease, Spastic paraplegia, intellectual disability, nystagmus, and obesity. Other alias names for this target include ankyrin repeat-rich membrane-spanning protein, kinase D-interacting substrate 220kDa, and kinase D-interacting substrate of 220 kDa.
The detection range for different KIDINS220 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.