SIGIRR ELISA kits are immunoassay tools for the measurement of the protein single Ig and TIR domain containing, which is encoded by the SIGIRR gene in humans. Functionally, this protein is known to act as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. The canonical protein structure is reported to have an amino acid length of 410 residues, a mass of 45.7 kDa, and is a member of the Interleukin-1 receptor protein family. It is known to be localized in the membrane and is reported to be mainly expressed in epithelial tissues such as kidney, lung and gut. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. Other alias names for this target include single Ig IL-1R-related molecule, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, single immunoglobulin domain IL1R1 related, and single Ig IL-1-related receptor.
Some SIGIRR ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 500 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.