POLG ELISA kits are immunoassay tools for the measurement of the protein DNA polymerase gamma, catalytic subunit, which is encoded by the POLG gene in humans. Functionally, this protein is reported to be involved in replication of mitochondrial DNA. The canonical protein structure is reported to have an amino acid length of 1239 residues, a mass of 139.6 kDa, and is a member of the DNA polymerase type-A protein family. It is known to be localized in the mitochondria. The POLG gene has been associated with the disease, Progressive external ophthalmoplegia with mitochondrial DNA deletions. Other alias names for this target include MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, and MDP1.
The detection range for different POLG ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.