DNMT3B ELISA kits are immunoassay tools for the measurement of the protein DNA methyltransferase 3 beta, which is encoded by the DNMT3B gene in humans. Functionally, this protein is known to be required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. The canonical protein structure is reported to have an amino acid length of 853 residues, a mass of 95.8 kDa, and is a member of the C5-methyltransferase protein family. It is known to be localized in the nucleus and is widely expressed across many tissue types. As many as 8 protein isoforms have been reported. The protein has been noted to be post-translationally sumoylated. The DNMT3B gene has been associated with the disease, Immunodeficiency-centromeric instability-facial anomalies syndrome. Other alias names for this target include ICF, ICF1, M.HsaIIIB, DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5-)-methyltransferase 3 beta, and FSHD4.
The detection range for different DNMT3B ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 150 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.