DNMT3A ELISA kits are immunoassay tools for the measurement of the protein DNA methyltransferase 3 alpha, which is encoded by the DNMT3A gene in humans. Functionally, this protein is known to be required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. The canonical protein structure is reported to have an amino acid length of 912 residues, a mass of 101.9 kDa, and is a member of the C5-methyltransferase protein family. It is known to be localized in the nucleus and cytoplasm. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally methylated and sumoylated. The DNMT3A gene has been associated with the disease, Tatton-Brown-Rahman syndrome. Other alias names for this target include HESJAS, M.HsaIIIA, TBRS, DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5-)-methyltransferase 3 alpha, and DNMT3A2.
Some DNMT3A ELISA kits can detect targets at levels as low as 0.15 ng/mL and as high as 300 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.