CDK8 ELISA kits are immunoassay tools for the measurement of the protein cyclin dependent kinase 8, which is encoded by the CDK8 gene in humans. Functionally, this protein is a known component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. The canonical protein structure is reported to have an amino acid length of 464 residues, a mass of 53.3 kDa, and is a member of the CMGC Ser/Thr protein kinase protein family. It is known to be localized in the nucleus. As many as 2 protein isoforms have been reported. The CDK8 gene has been associated with the disease, Intellectual developmental disorder with hypotonia and behavioral abnormalities. Other alias names for this target include K35, CDK8 protein kinase, cell division protein kinase 8, mediator complex subunit CDK8, mediator of RNA polymerase II transcription subunit CDK8, and IDDHBA.
Some CDK8 ELISA kits can detect targets at levels as low as 62.5 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.