ATP11C ELISA kits are immunoassay tools for the measurement of the protein ATPase phospholipid transporting 11C, which is encoded by the ATP11C gene in humans. Functionally, this protein is reported to be a catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of the plasma membrane. The canonical protein structure is reported to have an amino acid length of 1132 residues, a mass of 129.5 kDa, and is a member of the Cation transport ATPase (P-type) (TC 3.A.3) protein family. It is known to be localized in the ER and cell membrane and is widely expressed across many tissue types. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved and phosphorylated. The ATP11C gene has been associated with the disease, Hemolytic anemia. Other alias names for this target include ATPase, class VI, type 11C, P4-ATPase flippase complex alpha subunit ATP11C, probable phospholipid-transporting ATPase IG, and phospholipid-transporting ATPase IG.
The detection range for different ATP11C ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.