DIABLO ELISA kits are immunoassay tools for the measurement of the protein diablo IAP-binding mitochondrial protein, which is encoded by the DIABLO gene in humans. Functionally, this protein is reported to promote apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. The canonical protein structure is reported to have an amino acid sequence of 239 residues and a mass of 27.1 kDa. It is known to be localized in the mitochondria and is widely expressed across many tissue types. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated. The DIABLO gene has been associated with the disease, Deafness. Other alias names for this target include diablo-like protein, direct IAP-binding protein with low pI, second mitochondria-derived activator of caspase, and diablo homolog, mitochondrial.
The detection range for different DIABLO ELISA kits can vary, with some assays measuring target concentrations as low as 15.625 pg/mL and as high as 30 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.