KMT2D ELISA kits are immunoassay tools for the measurement of the protein lysine methyltransferase 2D, which is encoded by the KMT2D gene in humans. Functionally, this protein is a known histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). The canonical protein structure is reported to have an amino acid length of 5537 residues, a mass of 593.4 kDa, and is a member of the Histone-lysine methyltransferase protein family. It is known to be localized in the nucleus and is reported to be expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver. As many as 2 protein isoforms have been reported. The KMT2D gene has been associated with the disease, Kabuki syndrome. Other alias names for this target include AAD10 and ALR.
Some KMT2D ELISA kits can detect targets at levels as low as 1.56 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.