CD55 ELISA kits are immunoassay tools for the measurement of the protein CD55 molecule (Cromer blood group), which is encoded by the CD55 gene in humans. Functionally, this protein is known to recognize C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. The canonical protein structure is reported to have an amino acid length of 381 residues, a mass of 41.4 kDa, and is a member of the Receptors of complement activation (RCA) protein family. It is noted to be expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. As many as 7 protein isoforms have been reported. The protein has been noted to be post-translationally O-glycosylated. The CD55 gene has been associated with the disease, Complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy. Other alias names for this target include CR, DAF, TC, complement decay-accelerating factor, and CHAPLE.
The detection range for different CD55 ELISA kits can vary, with some assays measuring target concentrations as low as 5.47 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.