ATP13A2 ELISA kits are immunoassay tools for the measurement of the protein ATPase cation transporting 13A2, which is encoded by the ATP13A2 gene in humans. Functionally, this protein is known to be involved in autophagy pathways and the response to oxidative stress. The canonical protein structure is reported to have an amino acid length of 1180 residues, a mass of 128.8 kDa, and is a member of the Cation transport ATPase (P-type) (TC 3.A.3) protein family. It is known to be localized in the cytoplasmic vesicles and lysosomes and is reported to be expressed in the brain; protein levels are markedly increased in the brain from subjects with Parkinson disease and subjects with dementia with Lewy bodies. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated and glycosylated. The ATP13A2 gene has been associated with the disease, Kufor-Rakeb syndrome. Other alias names for this target include HSA9947, KRPPD, PARK9, SPG78, polyamine-transporting ATPase 13A2, ATPase 13A2, ATPase type 13A2, and CLN12.
The detection range for different ATP13A2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.312 ng/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.