UPF1 ELISA kits are immunoassay tools for the measurement of the protein UPF1 RNA helicase and ATPase, which is encoded by the UPF1 gene in humans. Functionally, this protein is known to be a RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. The canonical protein structure is reported to have an amino acid length of 1129 residues, a mass of 124.3 kDa, and is a member of the DNA2/NAM7 helicase protein family. It is known to be localized in the nucleus and cytoplasm and is ubiquitously expressed across many tissue types. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. Other alias names for this target include NORF1, RENT1, UTF, pNORF1, smg-2, regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, and HUPF1.
Some UPF1 ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.