POLA1 ELISA kits are immunoassay tools for the measurement of the protein DNA polymerase alpha 1, catalytic subunit, which is encoded by the POLA1 gene in humans. Functionally, this protein is a known catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. The canonical protein structure is reported to have an amino acid length of 1462 residues, a mass of 165.9 kDa, and is a member of the DNA polymerase type-B protein family. It is known to be localized in the nucleus and cytoplasm. The protein has been noted to be post-translationally cleaved. The POLA1 gene has been associated with the disease, Pigmentary disorder. Other alias names for this target include PDR, POLA, VEODS, p180, DNA polymerase alpha catalytic subunit, and NSX.
Some POLA1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.